Borchelt, David R : rechercher sur Z-Library

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1

Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium Hydroxide

Krewski, Daniel, Yokel, Robert A, Nieboer, Evert, Borchelt, David, Cohen, Joshua, Harry, Jean, Kacew, Sam, Lindsay, Joan, Mahfouz, Amal M, Rondeau, Virginie

Journal:

Journal of Toxicology and Environmental Health Part B

Année:

2007

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2007

2

MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

Florian L. Muller, Yuhong Liu, Amanda Jernigan, David Borchelt, Arlan Richardson, Holly Van Remmen

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 354 KB

english, 2008

3

Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker

Kevin Boylan, Cui Yang, Julia Crook, Karen Overstreet, Michael Heckman, Yong Wang, David Borchelt, Gerry Shaw

Journal:

Journal of Neurochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 362 KB

english, 2009

4

Are our animal models good enough?

Borchelt, David

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 49 KB

english, 2013

5

ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models

Price, Donald L., Tanzi, Rudolph E., Borchelt, David R., Sisodia, Sangram S.

Journal:

Annual Review of Genetics

Année:

1998

Langue:

english

Fichier:

PDF, 252 KB

english, 1998

6

Heterogeneity of Matrin 3 in the developing and aging murine central nervous system

Rayaprolu, Sruti, D'Alton, Simon, Crosby, Keith, Moloney, Christina, Howard, John, Duffy, Colin, Cabrera, Mariela, Siemienski, Zoe, Hernandez, Abigail R, Gallego-Iradi, Carolina, Borchelt, David R., L

Journal:

The Journal of Comparative Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 7.42 MB

english, 2016

7

Metabolic Therapy with Deanna Protocol Supplementation Delays Disease Progression and Extends Survival in Amyotrophic Lateral Sclerosis (ALS) Mouse Model

Ari, Csilla, Poff, Angela M., Held, Heather E., Landon, Carol S., Goldhagen, Craig R., Mavromates, Nicholas, D’Agostino, Dominic P., Borchelt, David R.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 542 KB

english, 2014

8

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

Ole A. Andreassen, Robert J. Ferrante, Hsueh-Meei Huang, Alpaslan Dedeoglu, Larry Park, Kimberly L. Ferrante, Jennifer Kwon, David R. Borchelt, Christopher A. Ross, Gary E. Gibson, M. Flint Beal

Journal:

Annals of Neurology

Année:

2001

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2001

9

Loss of functional prion protein: a role in prion disorders?

David R. Borchelt, Sangram S. Sisodia

Journal:

Chemistry & Biology

Année:

1996

Langue:

english

Fichier:

PDF, 504 KB

english, 1996

10

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

Joanna L Jankowsky, Hilda H Slunt, Tamara Ratovitski, Nancy A Jenkins, Neal G Copeland, David R Borchelt

Journal:

Biomolecular Engineering

Année:

2001

Langue:

english

Fichier:

PDF, 823 KB

english, 2001

11

Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states

Mercedes Prudencio, David R Borchelt

Journal:

Molecular Neurodegeneration

Année:

2011

Langue:

english

Fichier:

PDF, 837 KB

english, 2011

12

Investigation of RNA interference to suppress expression of full-length and fragment human huntingtin

Devin S. Gary, Abigail Davidson, Olivier Milhavet, Hilda Slunt, David R. Borchelt

Journal:

NeuroMolecular Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 421 KB

english, 2007

13

Transgenic mouse models of neurodegenerative disease: Opportunities for therapeutic development

Joanna L. Jankowsky, Alena Savonenko, Gabriele Schilling, Jiou Wang, Guilian Xu, David R. Borchelt

Journal:

Current Neurology and Neuroscience Reports

Année:

2002

Langue:

english

Fichier:

PDF, 599 KB

english, 2002

14

Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease

Bruce G. Jenkins, Ole A. Andreassen, Alpaslan Dedeoglu, Blair Leavitt, Michael Hayden, David Borchelt, Christopher A. Ross, Robert J. Ferrante, M. Flint Beal

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 307 KB

english, 2005

15

Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation

Jiou Wang, Guilian Xu, David R. Borchelt

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 318 KB

english, 2006

16

Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme

Mercedes Prudencio, Armando Durazo, Julian P. Whitelegge, David R. Borchelt

Journal:

Journal of Neurochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 431 KB

english, 2009

17

An examination of αB-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis

Celeste M. Karch, David R. Borchelt

Journal:

Journal of Neurochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 552 KB

english, 2010

18

The Value of Transgenic Models for the Study of Neurodegenerative Diseases

DONALD L. PRICE, PHILIP C. WONG, ALICJA L. MARKOWSKA, MICHAEL K. LEE, GOPAL THINAKAREN, DONALD W. CLEVELAND, SANGRAM S. SISODIA, DAVID R. BORCHELT

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 336 KB

english, 2000

19

Transgenic Mouse Models of Alzheimer's Disease and Amyotrophic Lateral Sclerosis

David R. Borchelt, Philip C. Wong, Sangram S. Sisodia, Donald L. Price

Journal:

Brain Pathology

Année:

1998

Langue:

english

Fichier:

PDF, 243 KB

english, 1998

20

10.1038/1196

Price, Donald L, Sisodia, Sangram S, Borchelt, David R

Journal:

Nature Genetics

Année:

1998

Langue:

english

Fichier:

PDF, 96 KB

english, 1998

21

10.1038/5715

Iadecola, Costantino, Zhang, Fangyi, Niwa, Kiyoshi, Eckman, Chris, Turner, Sherry K., Fischer, Elizabeth, Younkin, Steven, Borchelt, David R., Hsiao, Karen K., Carlson, George A.

Journal:

Nature Neuroscience

Année:

1999

Langue:

english

Fichier:

PDF, 193 KB

english, 1999

22

10.1038/85064

Cai, Huaibin, Wang, Yanshu, McCarthy, Diane, Wen, Hongjin, Borchelt, David R., Price, Donald L., Wong, Philip C.

Journal:

Nature Neuroscience

Année:

2001

Langue:

english

Fichier:

PDF, 778 KB

english, 2001

23

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

Lee, Michael K., Borchelt, David R., Kim, Grace, Thinakaran, Gopal, Slunt, Hilda H., Ratovitski, Tamara, Martin, Lee J., Kittur, Anik, Gandy, Samuel, Levey, Allan I.

Journal:

Nature Medicine

Année:

1997

Fichier:

PDF, 567 KB

1997

24

Genetically engineered mouse models of neurodegenerative diseases

Wong, Philip C., Cai, Huaibin, Borchelt, David R., Price, Donald L.

Journal:

Nature Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 357 KB

english, 2002

25

Genetically engineered models relevant to neurodegenerative disorders

Philip C. Wong, Huaibin Cai, David R. Borchelt, Donald L. Price

Journal:

Journal of Molecular Neuroscience

Année:

2001

Langue:

english

Fichier:

PDF, 289 KB

english, 2001

26

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding

Yunhua Shi, Richard A. Mowery, Jonathan Ashley, Michelle Hentz, Alejandro J. Ramirez, Basar Bilgicer, Hilda Slunt-Brown, David R. Borchelt, Bryan F. Shaw

Journal:

Protein Science

Année:

2012

Langue:

english

Fichier:

PDF, 4.93 MB

english, 2012

27

Transgenic and gene-targeting approaches to model disorders of motor neurons

Philip C. Wong, David R. Borchelt, Michael K. Lee, Carlos A. Pardo, Sangram S. Sisodia, Don W. Cleveland, Vassilis E. Koliatsos, Donald L. Price

Journal:

Seminars in Neuroscience

Année:

1996

Langue:

english

Fichier:

PDF, 106 KB

english, 1996

28

A vector for expressing foreign genes in the brains and hearts of transgenic mice

David R. Borchelt, Janine Davis, Marek Fischer, Micheal K. Lee, Hilda H. Slunt, Tamara Ratovitsky, Jean Regard, Neal G. Copeland, Nancy A. Jenkins, Sangram S. Sisodia, Donald L. Price

Journal:

Genetic Analysis: Biomolecular Engineering

Année:

1996

Langue:

english

Fichier:

PDF, 487 KB

english, 1996

29

Identifying new therapeutics for Huntington's disease

Gabriele Schilling, David R. Borchelt

Journal:

Clinical Neuroscience Research

Année:

2003

Langue:

english

Fichier:

PDF, 132 KB

english, 2003

30

Inherited Neurodegenerative Diseases and Transgenic Models

Donald L. Price, Mark W. Becher, Philip C. Wong, David R. Borchelt, Michael K. Lee, Sangram S. Sisodia

Journal:

Brain Pathology

Année:

1996

Langue:

english

Fichier:

PDF, 1.55 MB

english, 1996

31

Expression of stabilized β-catenin in differentiated neurons of transgenic mice does not result in tumor formation

John E Kratz, Duncan Stearns, David L Huso, Hilda H Slunt, Donald L Price, David R Borchelt, Charles G Eberhart

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 484 KB

english, 2002

32

Synaptic Transmission and Hippocampal Long-Term Potentiation in Transgenic Mice Expressing FAD-Linked Presenilin 1

Angèle Parent, David J. Linden, Sangram S. Sisodia, David R. Borchelt

Journal:

Neurobiology of Disease

Année:

1999

Langue:

english

Fichier:

PDF, 110 KB

english, 1999

33

Stable Association of Presenilin Derivatives and Absence of Presenilin Interactions with APP

Gopal Thinakaran, Jean B. Regard, Christopher M.L. Bouton, Christie L. Harris, Donald L. Price, David R. Borchelt, Sangram S. Sisodia

Journal:

Neurobiology of Disease

Année:

1998

Langue:

english

Fichier:

PDF, 314 KB

english, 1998

34

Axonal Transport of Mutant Superoxide Dismutase 1 and Focal Axonal Abnormalities in the Proximal Axons of Transgenic Mice

David R. Borchelt, Philip C. Wong, Mark W. Becher, Carlos A. Pardo, Michael K. Lee, Zuo-Shang Xu, Gopal Thinakaran, Nancy A. Jenkins, Neal G. Copeland, Sangram S. Sisodia, Don W. Cleveland, Donald L.

Journal:

Neurobiology of Disease

Année:

1998

Langue:

english

Fichier:

PDF, 957 KB

english, 1998

35

Enhanced Synaptic Potentiation in Transgenic Mice Expressing presenilin 1 Familial Alzheimer's Disease Mutation Is Normalized with a Benzodiazepine

Shahid H. Zaman, Angèle Parent, Aaron Laskey, Michael K. Lee, David R. Borchelt, Sangram S. Sisodia, Roberto Malinow

Journal:

Neurobiology of Disease

Année:

2000

Langue:

english

Fichier:

PDF, 245 KB

english, 2000

36

Creatine Increases Survival and Delays Motor Symptoms in a Transgenic Animal Model of Huntington's Disease

Ole A. Andreassen, Alpaslan Dedeoglu, Robert J. Ferrante, Bruce G. Jenkins, Kimberly L. Ferrante, Melissa Thomas, Avi Friedlich, Susan E. Browne, Gabriele Schilling, David R. Borchelt, Steven M. Hersc

Journal:

Neurobiology of Disease

Année:

2001

Langue:

english

Fichier:

PDF, 482 KB

english, 2001

37

High Molecular Weight Complexes of Mutant Superoxide Dismutase 1: Age-Dependent and Tissue-Specific Accumulation

Jiou Wang, Guilian Xu, David R. Borchelt

Journal:

Neurobiology of Disease

Année:

2002

Langue:

english

Fichier:

PDF, 296 KB

english, 2002

38

Fibrillar Inclusions and Motor Neuron Degeneration in Transgenic Mice Expressing Superoxide Dismutase 1 with a Disrupted Copper-Binding Site

Jiou Wang, Guilian Xu, Victoria Gonzales, Michael Coonfield, David Fromholt, Neal G. Copeland, Nancy A. Jenkins, David R. Borchelt

Journal:

Neurobiology of Disease

Année:

2002

Langue:

english

Fichier:

PDF, 675 KB

english, 2002

39

Asparagine-linked glycosylation of the scrapie and cellular prion proteins

Tokuko Haraguchi, Susan Fisher, Sigvard Olofsson, Tamao Endo, Darlene Groth, Anthony Tarentino, David R. Borchelt, David Teplow, Leroy Hood, Alma Burlingame, Erik Lycke, Akira Kobata, Stanley B. Prusi

Journal:

Archives of Biochemistry and Biophysics

Année:

1989

Langue:

english

Fichier:

PDF, 3.81 MB

english, 1989

40

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

Karen K. Hsiao, David R. Borchelt, Kristine Olson, Rosa Johannsdottir, Cheryl Kitt, Wael Yunis, Sherry Xu, Chris Eckman, Steven Younkin, Donald Price, Costantino Iadecola, H. Brent Clark, George Carls

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 3.46 MB

english, 1995

41

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Philip C Wong, Carlos A Pardo, David R Borchelt, Michael K Lee, Neal G Copeland, Nancy A Jenkins, Sangram S Sisodia, Don W Cleveland, Donald L Price

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 15.97 MB

english, 1995

42

Aggregation modulating elements in mutant human superoxide dismutase 1

Celeste M. Karch, David R. Borchelt

Journal:

Archives of Biochemistry and Biophysics

Année:

2010

Langue:

english

Fichier:

PDF, 952 KB

english, 2010

43

Cellular fusion for gene delivery to SCA1 affected Purkinje neurons

K. Amy Chen, Pedro E. Cruz, Derek J. Lanuto, Terence R. Flotte, David R. Borchelt, Arun Srivastava, Jianyi Zhang, Dennis A. Steindler, Tong Zheng

Journal:

Molecular and Cellular Neuroscience

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

44

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: Relationships to β-amyloid deposition and neurotransmitter abnormalities

Alena Savonenko, Guilian M. Xu, Tatiana Melnikova, Johanna L. Morton, Victoria Gonzales, Molly P.F. Wong, Donald L. Price, Fai Tang, Alicja L. Markowska, David R. Borchelt

Journal:

Neurobiology of Disease

Année:

2005

Langue:

english

Fichier:

PDF, 775 KB

english, 2005

45

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

Jiou Wang, Guilian Xu, Hilda H. Slunt, Victoria Gonzales, Michael Coonfield, David Fromholt, Neal G. Copeland, Nancy A. Jenkins, David R. Borchelt

Journal:

Neurobiology of Disease

Année:

2005

Langue:

english

Fichier:

PDF, 437 KB

english, 2005

46

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1

Joanna L Jankowsky, Hilda H Slunt, Victoria Gonzales, Nancy A Jenkins, Neal G Copeland, David R Borchelt

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 249 KB

english, 2004

47

Differential regulation of small heat shock proteins in transgenic mouse models of neurodegenerative diseases

Jiou Wang, Elizabeth Martin, Victoria Gonzales, David R. Borchelt, Michael K. Lee

Journal:

Neurobiology of Aging

Année:

2008

Langue:

english

Fichier:

PDF, 4.92 MB

english, 2008

48

Amyloid precursor protein increases cortical neuron size in transgenic mice

Esther S. Oh, Alena V. Savonenko, Julie F. King, Stina M. Fangmark Tucker, Gay L. Rudow, Guilian Xu, David R. Borchelt, Juan C. Troncoso

Journal:

Neurobiology of Aging

Année:

2009

Langue:

english

Fichier:

PDF, 181 KB

english, 2009

49

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

eMalick G. Njie, Ellen Boelen, Frank R. Stassen, Harry W.M. Steinbusch, David R. Borchelt, Wolfgang J. Streit

Journal:

Neurobiology of Aging

Année:

2012

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2012

50

Tetracycline-controlled expression of presenilin-1 in transgenic mice

Joanna L. Jankowsky, Hilda H. Slunt, David R. Borchelt

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 201 KB

english, 2000